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Poor outcome of pediatric B-cell acute lymphoblastic leukemia associated with high level of CRLF2 gene expression in distinct molecular subtypes

BACKGROUND: Overexpression of the cytokine receptor-like factor 2 (CRLF2) gene is the most common feature in the Philadelphia chromosome (Ph)-like subtype of B-cell acute lymphoblastic leukemia (B-ALL). However, the predictive value of CRLF2 overexpression for the prognosis of pediatric B-ALL patien...

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Detalles Bibliográficos
Autores principales: Lin, Danna, Yang, Keyan, Yu, Lihua, Huang, Lulu, Lai, Xiaorong, Wu, Li, Xia, Xiayu, Zhang, Jingwen, Zheng, Qinlong, Yang, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661883/
https://www.ncbi.nlm.nih.gov/pubmed/38023153
http://dx.doi.org/10.3389/fonc.2023.1256054