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The liver-derived exosomes stimulate insulin gene expression in pancreatic beta cells under condition of insulin resistance

INTRODUCTION: An insufficient functional beta cell mass is a core pathological hallmark of type 2 diabetes (T2D). Despite the availability of several effective pharmaceuticals for diabetes management, there is an urgent need for novel medications to protect pancreatic beta cells under diabetic condi...

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Detalles Bibliográficos
Autores principales: Mahmoudi-Aznaveh, Azam, Tavoosidana, Gholamreza, Najmabadi, Hossein, Azizi, Zahra, Ardestani, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661932/
https://www.ncbi.nlm.nih.gov/pubmed/38027137
http://dx.doi.org/10.3389/fendo.2023.1303930