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Multi-scale models of whole cells: progress and challenges

Whole-cell modeling is “the ultimate goal” of computational systems biology and “a grand challenge for 21st century” (Tomita, Trends in Biotechnology, 2001, 19(6), 205–10). These complex, highly detailed models account for the activity of every molecule in a cell and serve as comprehensive knowledge...

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Detalles Bibliográficos
Autores principales: Georgouli, Konstantia, Yeom, Jae-Seung, Blake, Robert C., Navid, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661945/
https://www.ncbi.nlm.nih.gov/pubmed/38020904
http://dx.doi.org/10.3389/fcell.2023.1260507