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A marine-derived fatty acid targets the cell membrane of Gram-positive bacteria

The rapid evolution of antibiotic resistance is shrinking our stockpile of commercially available antibiotics. Therefore, new antimicrobials with novel mechanisms of action (MoAs) are desperately needed. The free fatty acid, (Z)-13-methyltetra-4-decenoic acid ((Z)-4C-14:1), isolated from a marine se...

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Detalles Bibliográficos
Autores principales: Upender, Isha, Yoshida, Olivia, Schrecengost, Anna, Ranson, Hilary, Wu, Qihao, Rowley, David C., Kishore, Shreya, Cywes, Claire, Miller, Eric L., Whalen, Kristen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662121/
https://www.ncbi.nlm.nih.gov/pubmed/37905811
http://dx.doi.org/10.1128/jb.00310-23