In-silico and in-vitro functional validation of imidazole derivatives as potential sirtuin inhibitor

INTRODUCTION: Epigenetic enzymes can interact with a wide range of genes that actively participate in the progression or repression of a diseased condition, as they are involved in maintaining cellular homeostasis. Sirtuins are a family of Class III epigenetic modifying enzymes that regulate cellula...

Descripción completa

Detalles Bibliográficos
Autores principales: Dindi, Uma Maheswara Rao, Sadiq, Suhadha Parveen, Al-Ghamdi, Sameer, Alrudian, Naif Abdurhman, Dayel, Salman Bin, Abuderman, Abdulwahab Ali, Shahid, Mohammad, Ramesh, Thiyagarajan, Vilwanathan, Ravikumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662127/
https://www.ncbi.nlm.nih.gov/pubmed/38020163
http://dx.doi.org/10.3389/fmed.2023.1282820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662127/
https://www.ncbi.nlm.nih.gov/pubmed/38020163
http://dx.doi.org/10.3389/fmed.2023.1282820

Ejemplares similares