Cargando…
In-silico and in-vitro functional validation of imidazole derivatives as potential sirtuin inhibitor
INTRODUCTION: Epigenetic enzymes can interact with a wide range of genes that actively participate in the progression or repression of a diseased condition, as they are involved in maintaining cellular homeostasis. Sirtuins are a family of Class III epigenetic modifying enzymes that regulate cellula...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662127/ https://www.ncbi.nlm.nih.gov/pubmed/38020163 http://dx.doi.org/10.3389/fmed.2023.1282820 |