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Application of the HPLC-ELSD technique for the determination of major metabolites of ibuprofen and creatinine in human urine

The report presents robust and high throughput methods, based on liquid chromatography coupled with evaporative light scattering detection (HPLC-ELSD), for the simultaneous determination of major metabolites of ibuprofen (IBU), namely 2-hydroxyibuprofen and carboxyibuprofen (method A) as well as cre...

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Detalles Bibliográficos
Autores principales: Piechocka, Justyna, Matwiej, Natalia, Gaweł, Marta, Matyjaszczyk, Michał, Głowacki, Rafał, Chwatko, Grażyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662266/
https://www.ncbi.nlm.nih.gov/pubmed/37985716
http://dx.doi.org/10.1038/s41598-023-47594-8