Klotho inhibits IGF1R/PI3K/AKT signalling pathway and protects the heart from oxidative stress during ischemia/reperfusion injury

Ischemia/reperfusion injury (IRI) of the heart involves the activation of oxidative and proapoptotic pathways. Simultaneously Klotho protein presents anti-aging, antiapoptotic and antioxidative properties. Therefore, this study aimed to evaluate the effect of Klotho protein on oxidative stress in he...

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Detalles Bibliográficos
Autores principales: Olejnik, Agnieszka, Radajewska, Anna, Krzywonos-Zawadzka, Anna, Bil-Lula, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662387/
https://www.ncbi.nlm.nih.gov/pubmed/37985893
http://dx.doi.org/10.1038/s41598-023-47686-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662387/
https://www.ncbi.nlm.nih.gov/pubmed/37985893
http://dx.doi.org/10.1038/s41598-023-47686-5

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