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Early-to-mid stage idiopathic Parkinson’s disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females

Neuroinflammation in the brain contributes to the pathogenesis of Parkinson’s disease (PD), but the potential dysregulation of peripheral immunity has not been systematically investigated for idiopathic PD (iPD). Here we showed an elevated peripheral cytotoxic immune milieu, with more terminally-dif...

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Detalles Bibliográficos
Autores principales: Capelle, Christophe M., Ciré, Séverine, Hedin, Fanny, Hansen, Maxime, Pavelka, Lukas, Grzyb, Kamil, Kyriakis, Dimitrios, Hunewald, Oliver, Konstantinou, Maria, Revets, Dominique, Tslaf, Vera, Marques, Tainá M., Gomes, Clarissa P. C., Baron, Alexandre, Domingues, Olivia, Gomez, Mario, Zeng, Ni, Betsou, Fay, May, Patrick, Skupin, Alexander, Cosma, Antonio, Balling, Rudi, Krüger, Rejko, Ollert, Markus, Hefeng, Feng Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662447/
https://www.ncbi.nlm.nih.gov/pubmed/37985656
http://dx.doi.org/10.1038/s41467-023-43053-0