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Protective effects of macrophage-specific integrin α5 in myocardial infarction are associated with accentuated angiogenesis

Macrophages sense changes in the extracellular matrix environment through the integrins and play a central role in regulation of the reparative response after myocardial infarction. Here we show that macrophage integrin α5 protects the infarcted heart from adverse remodeling and that the protective...

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Detalles Bibliográficos
Autores principales: Li, Ruoshui, Chen, Bijun, Kubota, Akihiko, Hanna, Anis, Humeres, Claudio, Hernandez, Silvia C., Liu, Yang, Ma, Richard, Tuleta, Izabela, Huang, Shuaibo, Venugopal, Harikrishnan, Zhu, Fenglan, Su, Kai, Li, Jun, Zhang, Jinghang, Zheng, Deyou, Frangogiannis, Nikolaos G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662477/
https://www.ncbi.nlm.nih.gov/pubmed/37985764
http://dx.doi.org/10.1038/s41467-023-43369-x