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Can polygenic risk scores help explain disease prevalence differences around the world? A worldwide investigation

Complex disorders are caused by a combination of genetic, environmental and lifestyle factors, and their prevalence can vary greatly across different populations. The extent to which genetic risk, as identified by Genome Wide Association Study (GWAS), correlates to disease prevalence in different po...

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Detalles Bibliográficos
Autores principales: Jain, Pritesh R., Burch, Myson, Martinez, Melanie, Mir, Pablo, Fichna, Jakub P., Zekanowski, Cezary, Rizzo, Renata, Tümer, Zeynep, Barta, Csaba, Yannaki, Evangelia, Stamatoyannopoulos, John, Drineas, Petros, Paschou, Peristera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662565/
https://www.ncbi.nlm.nih.gov/pubmed/37986041
http://dx.doi.org/10.1186/s12863-023-01168-9