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Can polygenic risk scores help explain disease prevalence differences around the world? A worldwide investigation
Complex disorders are caused by a combination of genetic, environmental and lifestyle factors, and their prevalence can vary greatly across different populations. The extent to which genetic risk, as identified by Genome Wide Association Study (GWAS), correlates to disease prevalence in different po...
Autores principales: | Jain, Pritesh R., Burch, Myson, Martinez, Melanie, Mir, Pablo, Fichna, Jakub P., Zekanowski, Cezary, Rizzo, Renata, Tümer, Zeynep, Barta, Csaba, Yannaki, Evangelia, Stamatoyannopoulos, John, Drineas, Petros, Paschou, Peristera |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662565/ https://www.ncbi.nlm.nih.gov/pubmed/37986041 http://dx.doi.org/10.1186/s12863-023-01168-9 |
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