SEPSIS LEADS TO IMPAIRED MITOCHONDRIAL CALCIUM UPTAKE AND SKELETAL MUSCLE WEAKNESS BY REDUCING THE MICU1:MCU PROTEIN RATIO

Purpose: Intensive care unit–acquired weakness (ICUAW) is a severe neuromuscular complication that frequently occurs in patients with sepsis. The precise molecular pathophysiology of mitochondrial calcium uptake 1 (MICU1) and mitochondrial calcium uniporter (MCU) in ICUAW has not been fully elucidat...

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Detalles Bibliográficos
Autores principales: Li, Xuexin, Sun, Bowen, Li, Jie, Ye, Wanlin, Li, Mingjuan, Guan, Fasheng, Wu, Songlin, Luo, Xuerong, Feng, Jianguo, Jia, Jing, Liu, Xueru, Li, Tao, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Basic Science Aspects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662578/
https://www.ncbi.nlm.nih.gov/pubmed/37695737
http://dx.doi.org/10.1097/SHK.0000000000002221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662578/
https://www.ncbi.nlm.nih.gov/pubmed/37695737
http://dx.doi.org/10.1097/SHK.0000000000002221

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