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SEPSIS LEADS TO IMPAIRED MITOCHONDRIAL CALCIUM UPTAKE AND SKELETAL MUSCLE WEAKNESS BY REDUCING THE MICU1:MCU PROTEIN RATIO

Purpose: Intensive care unit–acquired weakness (ICUAW) is a severe neuromuscular complication that frequently occurs in patients with sepsis. The precise molecular pathophysiology of mitochondrial calcium uptake 1 (MICU1) and mitochondrial calcium uniporter (MCU) in ICUAW has not been fully elucidat...

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Detalles Bibliográficos
Autores principales:	Li, Xuexin, Sun, Bowen, Li, Jie, Ye, Wanlin, Li, Mingjuan, Guan, Fasheng, Wu, Songlin, Luo, Xuerong, Feng, Jianguo, Jia, Jing, Liu, Xueru, Li, Tao, Liu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Basic Science Aspects
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662578/ https://www.ncbi.nlm.nih.gov/pubmed/37695737 http://dx.doi.org/10.1097/SHK.0000000000002221

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