TNFα induces Caspase-3 activity in hematopoietic progenitor cells CD34+, CD33+, and CD41 + of myelodysplastic syndromes

BACKGROUND: Cytopenia is the primary feature of Myelodysplastic Syndrome, even in the presence of hypercellular bone marrow. TNFα is recognized as both a proinflammatory, and proapoptotic cytokine with a well established role in promoting apoptosis in MDS. Therefore, TNFα has the potential to be a v...

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Detalles Bibliográficos
Autores principales: Iriani, Anggraini, Rachman, Andhika, Setiabudy, Rahayuningsih D., Kresno, Siti B., Sudoyo, Aru W., Arief, Mansyur, Harahap, Alida R., Fatina, Marsya Kaila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662645/
https://www.ncbi.nlm.nih.gov/pubmed/37990142
http://dx.doi.org/10.1186/s12860-023-00495-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662645/
https://www.ncbi.nlm.nih.gov/pubmed/37990142
http://dx.doi.org/10.1186/s12860-023-00495-0

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