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TNFα induces Caspase-3 activity in hematopoietic progenitor cells CD34+, CD33+, and CD41 + of myelodysplastic syndromes

BACKGROUND: Cytopenia is the primary feature of Myelodysplastic Syndrome, even in the presence of hypercellular bone marrow. TNFα is recognized as both a proinflammatory, and proapoptotic cytokine with a well established role in promoting apoptosis in MDS. Therefore, TNFα has the potential to be a v...

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Detalles Bibliográficos
Autores principales:	Iriani, Anggraini, Rachman, Andhika, Setiabudy, Rahayuningsih D., Kresno, Siti B., Sudoyo, Aru W., Arief, Mansyur, Harahap, Alida R., Fatina, Marsya Kaila
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662645/ https://www.ncbi.nlm.nih.gov/pubmed/37990142 http://dx.doi.org/10.1186/s12860-023-00495-0

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