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Molecular design of stapled pentapeptides as building blocks of self-assembled coiled coil–like fibers

Peptide self-assembly inspired by natural superhelical coiled coils has been actively pursued but remains challenging due to limited helicity of short peptides. Side chain stapling can strengthen short helices but is unexplored in design of self-assembled helical nanofibers as it is unknown how stap...

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Detalles Bibliográficos
Autores principales: Jiang, Yixiang, Zhang, Wan, Yang, Fadeng, Wan, Chuan, Cai, Xiang, Liu, Jianbo, Zhang, Qianling, Li, Zigang, Han, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662664/
https://www.ncbi.nlm.nih.gov/pubmed/33523941
http://dx.doi.org/10.1126/sciadv.abd0492