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Evaluating pediatric tuberculosis dosing guidelines: A model-based individual data pooled analysis
BACKGROUND: The current World Health Organization (WHO) pediatric tuberculosis dosing guidelines lead to suboptimal drug exposures. Identifying factors altering the exposure of these drugs in children is essential for dose optimization. Pediatric pharmacokinetic studies are usually small, leading to...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662720/ https://www.ncbi.nlm.nih.gov/pubmed/37988391 http://dx.doi.org/10.1371/journal.pmed.1004303 |