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Evaluating pediatric tuberculosis dosing guidelines: A model-based individual data pooled analysis

BACKGROUND: The current World Health Organization (WHO) pediatric tuberculosis dosing guidelines lead to suboptimal drug exposures. Identifying factors altering the exposure of these drugs in children is essential for dose optimization. Pediatric pharmacokinetic studies are usually small, leading to...

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Detalles Bibliográficos
Autores principales: Galileya, Lufina Tsirizani, Wasmann, Roeland E., Chabala, Chishala, Rabie, Helena, Lee, Janice, Njahira Mukui, Irene, Hesseling, Anneke, Zar, Heather, Aarnoutse, Rob, Turkova, Anna, Gibb, Diana, Cotton, Mark F., McIlleron, Helen, Denti, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662720/
https://www.ncbi.nlm.nih.gov/pubmed/37988391
http://dx.doi.org/10.1371/journal.pmed.1004303