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Phosphorylation of AHR by PLK1 promotes metastasis of LUAD via DIO2-TH signaling

Metastasis of lung adenocarcinoma (LUAD) is a major cause of death in patients. Aryl hydrocarbon receptor (AHR), an important transcription factor, is involved in the initiation and progression of lung cancer. Polo-like kinase 1 (PLK1), a serine/threonine kinase, acts as an oncogene promoting the ma...

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Detalles Bibliográficos
Autores principales: Li, Chaohao, Allison, Derek B., He, Daheng, Mao, Fengyi, Wang, Xinyi, Rychahou, Piotr, Imam, Ibrahim A., Kong, Yifan, Zhang, Qiongsi, Zhang, Yanquan, Liu, Jinghui, Wang, Ruixin, Rao, Xiongjian, Wu, Sai, Evers, B. Mark, Shao, Qing, Wang, Chi, Li, Zhiguo, Liu, Xiaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662729/
https://www.ncbi.nlm.nih.gov/pubmed/37988371
http://dx.doi.org/10.1371/journal.pgen.1011017