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Intrinsically disordered regions are not sufficient to direct the compartmental localization of nucleolar proteins in the nucleus

The nucleolus is a non-membrane bound organelle central to ribosome biogenesis. The nucleolus contains a mix of proteins and RNA and has 3 known nucleolar compartments: the fibrillar center (FC), the dense fibrillar component (DFC), and the granular component (GC). The spatial organization of the nu...

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Detalles Bibliográficos
Autores principales: Lavering, Emily D., Gandhamaneni, Maunika, Weeks, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662738/
https://www.ncbi.nlm.nih.gov/pubmed/37943867
http://dx.doi.org/10.1371/journal.pbio.3002378