Cargando…

A zero-agnostic model for copy number evolution in cancer

MOTIVATION: New low-coverage single-cell DNA sequencing technologies enable the measurement of copy number profiles from thousands of individual cells within tumors. From this data, one can infer the evolutionary history of the tumor by modeling transformations of the genome via copy number aberrati...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmidt, Henri, Sashittal, Palash, Raphael, Benjamin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662746/
https://www.ncbi.nlm.nih.gov/pubmed/37943952
http://dx.doi.org/10.1371/journal.pcbi.1011590