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Defining the minimal components of the influenza A virus replication machinery via an in vitro reconstitution system

During influenza A virus infection, the viral RNA polymerase transcribes the viral negative-sense segmented RNA genome and replicates it in a two-step process via complementary RNA within viral ribonucleoprotein (vRNP) complexes. While numerous viral and host factors involved in vRNP functions have...

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Detalles Bibliográficos
Autores principales: Zhu, Zihan, Fan, Haitian, Fodor, Ervin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662765/
https://www.ncbi.nlm.nih.gov/pubmed/37943954
http://dx.doi.org/10.1371/journal.pbio.3002370