From X-inactivation to neurodevelopment: CHD8-transcription factors (TFs) competitive binding at regulatory regions of CHD8 target genes can contribute to correct neuronal differentiation

The chromodomain helicase DNA-binding protein 8 (CHD8) is a chromatin remodeler whose mutation is associated, with high penetrance, with autism. Individuals with CHD8 mutations share common symptoms such as autistic behaviour, cognitive impairment, schizophrenia comorbidity, and phenotypic features...

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Detalles Bibliográficos
Autores principales: Cerase, Andrea, Avner, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663126/
https://www.ncbi.nlm.nih.gov/pubmed/38020809
http://dx.doi.org/10.1016/j.crneur.2023.100114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663126/
https://www.ncbi.nlm.nih.gov/pubmed/38020809
http://dx.doi.org/10.1016/j.crneur.2023.100114

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