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Δ9-Tetrahydrocannabinol does not upregulate an aversive dopamine receptor mechanism in adolescent brain unlike in adults

Earlier age of cannabis usage poses higher risk of Cannabis Use Disorder and adverse consequences, such as addiction, anxiety, dysphoria, psychosis, largely attributed to its principal psychoactive component, Δ9-tetrahydrocannabinol (THC) and altered dopaminergic function. As dopamine D1-D2 receptor...

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Detalles Bibliográficos
Autores principales: Di Raddo, Marie-Eve, Milenkovic, Marija, Sivasubramanian, Meenalochani, Hasbi, Ahmed, Bergman, Jack, Withey, Sarah, Madras, Bertha K., George, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663137/
https://www.ncbi.nlm.nih.gov/pubmed/38020805
http://dx.doi.org/10.1016/j.crneur.2023.100107