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COX17 acetylation via MOF–KANSL complex promotes mitochondrial integrity and function

Reversible acetylation of mitochondrial proteins is a regulatory mechanism central to adaptive metabolic responses. Yet, how such functionally relevant protein acetylation is achieved remains unexplored. Here we reveal an unprecedented role of the MYST family lysine acetyltransferase MOF in energy m...

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Detalles Bibliográficos
Autores principales: Guhathakurta, Sukanya, Erdogdu, Niyazi Umut, Hoffmann, Juliane J., Grzadzielewska, Iga, Schendzielorz, Alexander, Seyfferth, Janine, Mårtensson, Christoph U., Corrado, Mauro, Karoutas, Adam, Warscheid, Bettina, Pfanner, Nikolaus, Becker, Thomas, Akhtar, Asifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663164/
https://www.ncbi.nlm.nih.gov/pubmed/37813994
http://dx.doi.org/10.1038/s42255-023-00904-w