Cytochrome P450 activity in rheumatoid arthritis patients during continuous IL-6 receptor antagonist therapy

ABSTRACT: BACKGROUND: Inflammation suppresses cytochrome P450 (CYP) enzyme activity, and single-dose interleukin 6 receptor antagonists (anti-IL-6R) reverse this effect. Here, we assess the impact of continuous anti-IL-6R therapy in patients with rheumatoid arthritis. METHODS: In a clinical pharmaco...

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Detalles Bibliográficos
Autores principales: Dunvald, Ann-Cathrine Dalgård, Søltoft, Kasper, Sheetal, Ekta, Just, Søren Andreas, Frederiksen, Ida Emilie Brejning, Nielsen, Flemming, Olsen, Dorte Aalund, Madsen, Jonna Skov, Hendricks, Oliver, Stage, Tore Bjerregaard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663184/
https://www.ncbi.nlm.nih.gov/pubmed/37831074
http://dx.doi.org/10.1007/s00228-023-03578-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663184/
https://www.ncbi.nlm.nih.gov/pubmed/37831074
http://dx.doi.org/10.1007/s00228-023-03578-1

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