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Cytochrome P450 activity in rheumatoid arthritis patients during continuous IL-6 receptor antagonist therapy
ABSTRACT: BACKGROUND: Inflammation suppresses cytochrome P450 (CYP) enzyme activity, and single-dose interleukin 6 receptor antagonists (anti-IL-6R) reverse this effect. Here, we assess the impact of continuous anti-IL-6R therapy in patients with rheumatoid arthritis. METHODS: In a clinical pharmaco...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663184/ https://www.ncbi.nlm.nih.gov/pubmed/37831074 http://dx.doi.org/10.1007/s00228-023-03578-1 |