Buprenorphine plasma and cerebrospinal fluid concentrations in osteoarthritis patients during low-dose transdermal patch dosing

METHODS: Fifty-six (56) patients scheduled for arthroplasty, received 7-day extended-release buprenorphine transdermal patches (5 µg/h) for five consecutive weeks, starting two weeks prior to the surgery. Simultaneous plasma and cerebrospinal fluid (CSF) samples were collected during spinal anesthes...

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Detalles Bibliográficos
Autores principales: Härkänen, Lasse, Hakomäki, Henriikka, Huopio, Jukka, Kokki, Hannu, Korhonen, Sanni, Lehtonen, Marko, Sjövall, Sari, Kokki, Merja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663223/
https://www.ncbi.nlm.nih.gov/pubmed/37864723
http://dx.doi.org/10.1007/s00228-023-03583-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663223/
https://www.ncbi.nlm.nih.gov/pubmed/37864723
http://dx.doi.org/10.1007/s00228-023-03583-4

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