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Buprenorphine plasma and cerebrospinal fluid concentrations in osteoarthritis patients during low-dose transdermal patch dosing

METHODS: Fifty-six (56) patients scheduled for arthroplasty, received 7-day extended-release buprenorphine transdermal patches (5 µg/h) for five consecutive weeks, starting two weeks prior to the surgery. Simultaneous plasma and cerebrospinal fluid (CSF) samples were collected during spinal anesthes...

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Detalles Bibliográficos
Autores principales:	Härkänen, Lasse, Hakomäki, Henriikka, Huopio, Jukka, Kokki, Hannu, Korhonen, Sanni, Lehtonen, Marko, Sjövall, Sari, Kokki, Merja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663223/ https://www.ncbi.nlm.nih.gov/pubmed/37864723 http://dx.doi.org/10.1007/s00228-023-03583-4

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