Thalamic Foxp2 regulates output connectivity and sensory-motor impairments in a model of Huntington’s Disease

BACKGROUND: Huntington's Disease (HD) is a disorder that affects body movements. Altered glutamatergic innervation of the striatum is a major hallmark of the disease. Approximately 30% of those glutamatergic inputs come from thalamic nuclei. Foxp2 is a transcription factor involved in cell diff...

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Detalles Bibliográficos
Autores principales: Rodríguez-Urgellés, Ened, Casas-Torremocha, Diana, Sancho-Balsells, Anna, Ballasch, Iván, García-García, Esther, Miquel-Rio, Lluis, Manasanch, Arnau, del Castillo, Ignacio, Chen, Wanqi, Pupak, Anika, Brito, Veronica, Tornero, Daniel, Rodríguez, Manuel J., Bortolozzi, Analia, Sanchez-Vives, Maria V., Giralt, Albert, Alberch, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663254/
https://www.ncbi.nlm.nih.gov/pubmed/37987826
http://dx.doi.org/10.1007/s00018-023-05015-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663254/
https://www.ncbi.nlm.nih.gov/pubmed/37987826
http://dx.doi.org/10.1007/s00018-023-05015-z

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