Intrinsic Resistance to Osimertinib in EGFR Mutated NSCLC Cell Lines Induced by Alteration in Cell-Cycle Regulators

BACKGROUND: Cell-cycle regulators are mutated in approximately 40% of all cancer types and have already been linked to worse outcomes in non-small cell lung cancer adenocarcinomas treated with osimertinib. However, their exact role in osimertinib resistance has not been elucidated. OBJECTIVE: In thi...

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Detalles Bibliográficos
Autores principales: Volta, Francesco, La Monica, Silvia, Leonetti, Alessandro, Gnetti, Letizia, Bonelli, Mara, Cavazzoni, Andrea, Fumarola, Claudia, Galetti, Maricla, Eltayeb, Kamal, Minari, Roberta, Petronini, Pier Giorgio, Tiseo, Marcello, Alfieri, Roberta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663255/
https://www.ncbi.nlm.nih.gov/pubmed/37855989
http://dx.doi.org/10.1007/s11523-023-01005-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663255/
https://www.ncbi.nlm.nih.gov/pubmed/37855989
http://dx.doi.org/10.1007/s11523-023-01005-0

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