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Tumor cell cytoplasmic metallothionein expression associates with differential tumor immunogenicity and prognostic outcome in high-grade serous ovarian carcinoma

BACKGROUND: The underlying mechanism of high T-cell presence as a favorable prognostic factor in high-grade serous ovarian carcinoma (HGSOC) is not yet understood. In addition to immune cells, various cofactors are essential for immune processes. One of those are metallothioneins (MTs), metal-bindin...

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Detalles Bibliográficos
Autores principales: Mairinger, Elena, Wessolly, Michael, Buderath, Paul, Borchert, Sabrina, Henrich, Larissa, Mach, Pawel, Steinborn, Julia, Kimming, Rainer, Jasani, Bharat, Schmid, Kurt Werner, Bankfalvi, Agnes, Mairinger, Fabian Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663300/
https://www.ncbi.nlm.nih.gov/pubmed/38023247
http://dx.doi.org/10.3389/fonc.2023.1252700