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Upregulation of LRRK2 following traumatic brain injury does not directly phosphorylate Thr(175) tau

Phosphorylated microtubule-associated protein tau (tau) aggregates are a pathological hallmark of various neurodegenerative diseases, including chronic traumatic encephalopathy and amyotrophic lateral sclerosis with cognitive impairment. While there are many residues phosphorylated on tau, phosphory...

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Detalles Bibliográficos
Autores principales: Donison, Neil, Hintermayer, Matthew, Subramaniam, Maegha, Santandrea, Erin, Volkening, Kathryn, Strong, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663351/
https://www.ncbi.nlm.nih.gov/pubmed/38026695
http://dx.doi.org/10.3389/fncel.2023.1272899