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A novel Glycyrrhiza glabra extract liquiritin targeting NFATc1 activity and ROS levels to counteract ovariectomy-induced osteoporosis and bone loss in murine model

Osteoporosis, a prevalent osteolytic condition worldwide, necessitates effective strategies to inhibit excessive bone resorption by curbing osteoclast hyperactivation. Liquiritin (LIQ), an flavanone derivative employed in acute lung injury and rheumatoid arthritis treatment, possesses an unclear rol...

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Detalles Bibliográficos
Autores principales: Hong, Guoju, Zhou, Lin, Zheng, Guanqiang, Zheng, Xiaoxia, Chen, Zhenqiu, He, Wei, Wei, Qiushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663366/
https://www.ncbi.nlm.nih.gov/pubmed/38026985
http://dx.doi.org/10.3389/fphar.2023.1287827