Brain metastasis, EGFR mutation subtype and generation of EGFR-TKI jointly influence the treatment outcome of patient with EGFR-mutant NSCLC

Non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutation is brain metastasis (BM)-prone. We determined the impact of this hallmark, along with EGFR subtype and generation of tyrosine kinase inhibitor (TKI) treatment, on patients’ outcome. 553 metastatic EGFR-mutant NS...

Descripción completa

Detalles Bibliográficos
Autores principales: Ju, Jia-Shiuan, Huang, Allen Chung-Cheng, Tung, Pi-Hung, Huang, Chi-Hsien, Chiu, Tzu-Hsuan, Wang, Chin-Chou, Ko, How-Wen, Chung, Fu-Tsai, Hsu, Ping-Chih, Fang, Yueh-Fu, Guo, Yi-Ke, Kuo, Chih-Hsi Scott, Yang, Cheng-Ta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663477/
https://www.ncbi.nlm.nih.gov/pubmed/37989860
http://dx.doi.org/10.1038/s41598-023-45815-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663477/
https://www.ncbi.nlm.nih.gov/pubmed/37989860
http://dx.doi.org/10.1038/s41598-023-45815-8

Ejemplares similares