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Insight into the on/off switch that regulates expression of the MSMEG-3762/63 efflux pump in Mycobacterium smegmatis

Drug resistance is one of the most difficult challenges facing tuberculosis (TB) control. Drug efflux is among the mechanisms leading to drug resistance. In our previous studies, we partially characterized the ABC-type MSMEG-3762/63 efflux pump in Mycobacterium smegmatis, which shares high percentag...

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Detalles Bibliográficos
Autores principales: Campolattano, Nicoletta, D’Abrosca, Gianluca, Russo, Luigi, De Siena, Barbara, Della Gala, Milena, De Chiara, Ida, Marasco, Rosangela, Goff, Aaron, Waddell, Simon J., Sacco, Margherita, Muscariello, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663510/
https://www.ncbi.nlm.nih.gov/pubmed/37989843
http://dx.doi.org/10.1038/s41598-023-47695-4