A common pathway for detergent-assisted oligomerization of Aβ42

Amyloid beta (Aβ) aggregation is a slow process without seeding or assisted nucleation. Sodium dodecyl sulfate (SDS) micelles stabilize Aβ42 small oligomers (in the dimer to tetramer range); subsequent SDS removal leads to a 150-kD Aβ42 oligomer. Dodecylphosphorylcholine (DPC) micelles also stabiliz...

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Detalles Bibliográficos
Autores principales: Muhammedkutty, Fidha Nazreen Kunnath, Prasad, Ramesh, Gao, Yuan, Sudarshan, Tarunya Rao, Robang, Alicia S., Watzlawik, Jens O., Rosenberry, Terrone L., Paravastu, Anant K., Zhou, Huan-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663524/
https://www.ncbi.nlm.nih.gov/pubmed/37989804
http://dx.doi.org/10.1038/s42003-023-05556-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663524/
https://www.ncbi.nlm.nih.gov/pubmed/37989804
http://dx.doi.org/10.1038/s42003-023-05556-w

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