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3,4-dimethoxychalcone induces autophagy and reduces neointimal hyperplasia and aortic lesions in mouse models of atherosclerosis

Autophagy inducers can prevent cardiovascular aging and age-associated diseases including atherosclerosis. Therefore, we hypothesized that autophagy-inducing compounds that act on atherosclerosis-relevant cells might have a protective role in the development of atherosclerosis. Here we identified 3,...

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Detalles Bibliográficos
Autores principales: Cerrato, Giulia, Alvarez-Lucena, Carlota, Sauvat, Allan, Hu, Yanhua, Forveille, Sabrina, Chen, Guo, Durand, Sylvère, Aprahamian, Fanny, Leduc, Marion, Motiño, Omar, Boscá, Lisardo, Xu, Qingbo, Kepp, Oliver, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663525/
https://www.ncbi.nlm.nih.gov/pubmed/37989732
http://dx.doi.org/10.1038/s41419-023-06305-x