Molecular dynamics of JUNO-IZUMO1 complexation suggests biologically relevant mechanisms in fertilization

JUNO-IZUMO1 binding is the first known physical link created between the sperm and egg membranes in fertilization, however, how this initiates sperm-egg fusion remains elusive. As advanced structural insights will help to combat the infertility crisis, or advance fertility control, we employed all-a...

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Detalles Bibliográficos
Autores principales: Pacak, Paulina, Kluger, Carleen, Vogel, Viola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663542/
https://www.ncbi.nlm.nih.gov/pubmed/37990051
http://dx.doi.org/10.1038/s41598-023-46835-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663542/
https://www.ncbi.nlm.nih.gov/pubmed/37990051
http://dx.doi.org/10.1038/s41598-023-46835-0

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