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Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice

Schistosomiasis is a parasitic disease affecting more than 250 million people worldwide. The transcription factor c-Jun, which is induced in S. mansoni infection-associated liver disease, can promote hepatocyte survival but can also trigger hepatocellular carcinogenesis. We aimed to analyze the hepa...

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Detalles Bibliográficos
Autores principales: Härle, Lukas, von Bülow, Verena, Knedla, Lukas, Stettler, Frederik, Müller, Heike, Zahner, Daniel, Haeberlein, Simone, Windhorst, Anita, Tschuschner, Annette, Burg-Roderfeld, Monika, Köhler, Kernt, Grevelding, Christoph G., Roeb, Elke, Roderfeld, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663609/
https://www.ncbi.nlm.nih.gov/pubmed/37990129
http://dx.doi.org/10.1038/s41598-023-47646-z