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Ca(V)3.1 channels facilitate calcium wave generation and myogenic tone development in mouse mesenteric arteries

The arterial myogenic response to intraluminal pressure elicits constriction to maintain tissue perfusion. Smooth muscle [Ca(2+)] is a key determinant of constriction, tied to L-type (Ca(V)1.2) Ca(2+) channels. While important, other Ca(2+) channels, particularly T-type could contribute to pressure...

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Detalles Bibliográficos
Autores principales: El-Lakany, Mohammed A., Haghbin, Nadia, Arora, Naman, Hashad, Ahmed M., Mironova, Galina Yu., Sancho, Maria, Gros, Robert, Welsh, Donald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663617/
https://www.ncbi.nlm.nih.gov/pubmed/37989780
http://dx.doi.org/10.1038/s41598-023-47715-3