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Babesia BdFE1 esterase is required for the anti-parasitic activity of the ACE inhibitor fosinopril

Effective and safe therapies for the treatment of diseases caused by intraerythrocytic parasites are impeded by the rapid emergence of drug resistance and the lack of novel drug targets. One such disease is human babesiosis, which is a rapidly emerging tick-borne illness caused by Babesia parasites....

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Detalles Bibliográficos
Autores principales: Vydyam, Pratap, Choi, Jae-Yeon, Gihaz, Shalev, Chand, Meenal, Gewirtz, Meital, Thekkiniath, Jose, Lonardi, Stefano, Gennaro, Joseph C., Ben Mamoun, Choukri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663679/
https://www.ncbi.nlm.nih.gov/pubmed/37797695
http://dx.doi.org/10.1016/j.jbc.2023.105313