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Babesia BdFE1 esterase is required for the anti-parasitic activity of the ACE inhibitor fosinopril
Effective and safe therapies for the treatment of diseases caused by intraerythrocytic parasites are impeded by the rapid emergence of drug resistance and the lack of novel drug targets. One such disease is human babesiosis, which is a rapidly emerging tick-borne illness caused by Babesia parasites....
Autores principales: | Vydyam, Pratap, Choi, Jae-Yeon, Gihaz, Shalev, Chand, Meenal, Gewirtz, Meital, Thekkiniath, Jose, Lonardi, Stefano, Gennaro, Joseph C., Ben Mamoun, Choukri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663679/ https://www.ncbi.nlm.nih.gov/pubmed/37797695 http://dx.doi.org/10.1016/j.jbc.2023.105313 |
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