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Structural basis of membrane machines that traffick and attach heme to cytochromes

We evaluate cryoEM and crystal structures of two molecular machines that traffick heme and attach it to cytochrome c (cyt c), the second activity performed by a cyt c synthase. These integral membrane proteins, CcsBA and CcmF/H, both covalently attach heme to cyt c, but carry it out via different me...

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Detalles Bibliográficos
Autores principales: Huynh, Jonathan Q., Lowder, Ethan P., Kranz, Robert G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663686/
https://www.ncbi.nlm.nih.gov/pubmed/37827288
http://dx.doi.org/10.1016/j.jbc.2023.105332