Exogenous NADPH exerts a positive inotropic effect and enhances energy metabolism via SIRT3 in pathological cardiac hypertrophy and heart failure

BACKGROUND: Therapies are urgently required to ameliorate pathological cardiac hypertrophy and enhance cardiac function in heart failure. Our preliminary experiments have demonstrated that exogenous NADPH exhibits a positive inotropic effect on isolated heart. This study aims to investigate the posi...

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Detalles Bibliográficos
Autores principales: Qian, Ke, Tang, Jie, Ling, Yue-Juan, Zhou, Ming, Yan, Xin-Xin, Xie, Yu, Zhu, Lu-Jia, Nirmala, Koju, Sun, Kang-Yun, Qin, Zheng-Hong, Sheng, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663691/
https://www.ncbi.nlm.nih.gov/pubmed/37950995
http://dx.doi.org/10.1016/j.ebiom.2023.104863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663691/
https://www.ncbi.nlm.nih.gov/pubmed/37950995
http://dx.doi.org/10.1016/j.ebiom.2023.104863

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