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Binding asymmetry and conformational studies of the AtGSDA dimer

Guanosine deaminase (GSDA) is an important deaminase that converts guanosine to xanthosine, a key intermediate in nitrogen recycling in plants. We previously solved complex structures of Arabidopsis thaliana GSDA bound by various ligands and examined its catalytic mechanism. Here, we report cocrysta...

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Detalles Bibliográficos
Autores principales: Jia, Qian, Zeng, Hui, Li, Mingwei, Tang, Jing, Xiao, Nan, Gao, Shangfang, Li, Huanxi, Zhang, Jinbing, Zhang, Zhiyong, Xie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663702/
https://www.ncbi.nlm.nih.gov/pubmed/38022696
http://dx.doi.org/10.1016/j.csbj.2023.11.004