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Human pluripotent stem cell fate trajectories toward lung and hepatocyte progenitors
In this study, we interrogate molecular mechanisms underlying the specification of lung progenitors from human pluripotent stem cells (hPSCs). We employ single-cell RNA-sequencing with high temporal precision, alongside an optimized differentiation protocol, to elucidate the transcriptional hierarch...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663741/ https://www.ncbi.nlm.nih.gov/pubmed/38026193 http://dx.doi.org/10.1016/j.isci.2023.108205 |