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Human pluripotent stem cell fate trajectories toward lung and hepatocyte progenitors

In this study, we interrogate molecular mechanisms underlying the specification of lung progenitors from human pluripotent stem cells (hPSCs). We employ single-cell RNA-sequencing with high temporal precision, alongside an optimized differentiation protocol, to elucidate the transcriptional hierarch...

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Detalles Bibliográficos
Autores principales: Ori, Chaido, Ansari, Meshal, Angelidis, Ilias, Olmer, Ruth, Martin, Ulrich, Theis, Fabian J., Schiller, Herbert B., Drukker, Micha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663741/
https://www.ncbi.nlm.nih.gov/pubmed/38026193
http://dx.doi.org/10.1016/j.isci.2023.108205