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Derived myeloid lineage induced pluripotent stem as a platform to study human C-C chemokine receptor type 5Δ32 homozygotes

The C-C chemokine receptor type 5 (CCR5) expressed on immune cells supports inflammatory responses by directing cells to the inflammation site. CCR5 is also a major coreceptor for macrophage tropic human immunodeficiency viruses (R5-HIV-1) and its variants can confer protection from HIV infection, m...

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Detalles Bibliográficos
Autores principales: Chen, Guibin, Calcaterra, Francesca, Ma, Yuchi, Ping, Xianfeng, Pontarini, Elena, Yang, Dan, Oriolo, Ferdinando, Yu, Zhen, Cancellara, Assunta, Mikulak, Joanna, Huang, Yuting, Della Bella, Silvia, Liu, Yangtengyu, Biesecker, Leslie G., Harper, Rebecca L., Dalgard, Clifton L., Boehm, Manfred, Mavilio, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663745/
https://www.ncbi.nlm.nih.gov/pubmed/38026202
http://dx.doi.org/10.1016/j.isci.2023.108331