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The PI3K-AKT-mTOR signaling pathway mediates the cytoskeletal remodeling and epithelial-mesenchymal transition in bladder outlet obstruction

OBJECTIVE: Partial bladder outlet obstruction(pBOO) is the most common cause of lower urinary tract symptoms (LUTS) and significantly affects the quality of life. Long-term pBOO can cause changes in bladder structure and function, referred to as bladder remodeling. The pathogenesis of pBOO-induced b...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaoxia, Zhanghuang, Chenghao, Mi, Tao, Jin, Liming, Liu, Jiayan, Li, Maoxian, Wu, Xin, Wang, Jinkui, Li, Mujie, Wang, Zhang, Guo, Peng, He, Dawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663759/
https://www.ncbi.nlm.nih.gov/pubmed/38027933
http://dx.doi.org/10.1016/j.heliyon.2023.e21281