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Xport-A functions as a chaperone by stabilizing the first five transmembrane domains of rhodopsin-1

Rhodopsin-1 (Rh1), the main photosensitive protein of Drosophila, is a seven-transmembrane domain protein, which is inserted co-translationally in the endoplasmic reticulum (ER) membrane. Biogenesis of Rh1 occurs in the ER, where various chaperones interact with Rh1 to aid in its folding and subsequ...

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Detalles Bibliográficos
Autores principales: Gaspar, Catarina J., Gomes, Tiago, Martins, Joana C., Melo, Manuel N., Adrain, Colin, Cordeiro, Tiago N., Domingos, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663829/
https://www.ncbi.nlm.nih.gov/pubmed/38025784
http://dx.doi.org/10.1016/j.isci.2023.108309